GAINESVILLE, Fla., Nov. 10, 2026 /PRNewswire/ -- Advita Ortho, a global medical technology leader, today announced first surgeries in Japan using the Vantage® Total Ankle Fixed Bearing System, including the Activit-E® polyethylene liner. The milestone expands Advita's international reach, bringing advanced ankle replacement solutions to Japanese surgeons and broadening treatment options for patients with ankle arthritis.

The surgeries were performed across Japan by Prof. Katsunori Ikari, MD, PhD, and Koichiro Yano, MD, at Tokyo's Women's Medical University Hospital and Prof. Kazuya Ikoma, MD, PhD, at Kyoto's Koseikai Takeda Hospital. 

"I'm honored to be among the first surgeons to use the landmark Vantage Total Ankle System in Japan," said Prof. Ikari. "The system's 10-year legacy of strong clinical data and outcomes provides my patients and me with confidence, and I look forward to seeing their progress post-surgery." 

The Vantage Ankle first launched in the U.S in 2016 with a low-profile tibial component, polyethylene liner, unique locking clip and curved talus implant. Its design goals were straightforward: address subsidence, implant loosening, bone cysts, instability, polyethylene revision and impingement. 

Advita's Vantage Ankle is now available in Japan with Activit-E, a next-generation highly crosslinked polyethylene with vitamin E antioxidant stabilization. Activit-E features a unique manufacturing process that replaces gamma irradiation crosslinking with peroxide crosslinking and adds vitamin E to provide strength, flexibility, toughness and oxidative stability.^1-2

"The introduction of Vantage Ankle in Japan marks an exciting milestone in Advita's global expansion of ankle solutions," said Aurelio Sahagun, CEO of Advita Ortho. "With more than a decade of clinical use and over 11,000 cases worldwide, we are proud to bring our flagship ankle system to Japan. This new market reflects our commitment to empowering surgeons with advanced solutions and broadening treatment options for patients."

Learn more about the Vantage Ankle and Advita's full suite of foot and ankle solutions at https://advita.com/foot-and-ankle/.  

References: 

1. Knight, J et al. Blended and Warm Irradiated vs. Infused: Mechanical Properties of Vitamin E Crosslinked UHMWPEs. ORS 2017 Annual Meeting. Poster No. 2034.
2. Muratoglu, O et al. Di‐cumyl peroxide cross‐linked UHMWPE/vitamin‐E blend for total joint arthroplasty implants. Journal of Orthopaedic Research. DOI: 10.1002/jor.25679.

The Vantage Ankle is distributed by Advita Ortho, LLC. Visit advita.com for information on product availability in your country.

About Advita Ortho
Advita Ortho is a global medical device company committed to advancing patients' lives through innovative orthopedic solutions. We specialize in high-quality implants and a comprehensive suite of integrated surgical technologies that are powered by data, artificial intelligence and machine learning. Offering trusted leadership and clinical expertise, Advita Ortho is uniquely positioned to advance mobility and improve lives worldwide. Learn more at www.advita.com and connect with us on LinkedIn, X and Instagram.

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SOURCE Advita Ortho, LLC